Successful Management of a Periaortic Graft Abscess After DeBakey Type I Aortic Dissection Repair: A Case Report

Authors

DOI:

https://doi.org/10.66636/gmj.v1.i2.a118

Keywords:

redo surgery, aortic graft infection, periaortic abscess, ascending aorta, DeBakey dissection, cardiac surgery, prosthetic graft infection

Abstract

Background  Periaortic and aortic graft infections (AGI) following thoracic aortic reconstruction are uncommon complications with reported mortality of 25–75% and limited standardised treatment guidance, with debate between graft preservation and complete explantation.

Case presentation  A 61-year-old man with type 2 diabetes and obesity (body mass index 41 kg/m²) underwent supracoronary ascending aorta and complete aortic arch replacement for DeBakey type I (Stanford A) acute aortic dissection. Five months postoperatively, recurrent high-grade fever and Pseudomonas aeruginosa bacteraemia developed despite carbapenem therapy. Contrast-enhanced CT demonstrated a progressive perigraft infiltrative collection contiguous with both prosthetic grafts. Redo sternotomy was performed with abscess evacuation and complete replacement of both ascending and arch grafts; intraoperative cultures again grew P. aeruginosa. The patient was discharged on day 30 with culture-directed lifelong ciprofloxacin; follow-up CT confirmed clearance.

Discussion  The case fulfilled two MAGIC major criteria (radiologic and microbiologic) and one minor (clinical), confirming AGI. Decisions between graft preservation and complete explantation depend on infection chronology and pathogen virulence; for early-onset deep mediastinal involvement with virulent gram-negative pathogens, complete graft excision combined with prolonged culture-directed antibiotic therapy was the most reliable strategy in this patient.

Conclusion  Successful management of periaortic graft abscess after thoracic aortic reconstruction requires high clinical suspicion, MAGIC-criteria-anchored diagnosis, complete graft explantation when infection is established, culture-directed antibiotic therapy, and structured long-term surveillance.

Keywords  aortic graft infection; periaortic abscess; aortic dissection; DeBakey type I; Pseudomonas aeruginosa; redo cardiac surgery; mediastinitis; MAGIC criteria

References

1. Chakfé N, Diener H, Lejay A, Assadian O, Berard X, Caillon J, et al. Editor's Choice — European Society for Vascular Surgery (ESVS) 2020 Clinical Practice Guidelines on the Management of Vascular Graft and Endograft Infections. Eur J Vasc Endovasc Surg. 2020;59(3):339–84. https://doi.org/10.1016/j.ejvs.2019.10.016

2. Wilson WR, Bower TC, Creager MA, Amin-Hanjani S, O'Gara PT, Lockhart PB, et al. Vascular graft infections, mycotic aneurysms, and endovascular infections: a scientific statement from the American Heart Association. Circulation. 2016;134(20):e412–60. https://doi.org/10.1161/CIR.0000000000000457

3. Lyons OTA, Baguneid M, Barwick TD, Bell RE, Foster N, Homer-Vanniasinkam S, et al. Diagnosis of aortic graft infection: a case definition by the Management of Aortic Graft Infection Collaboration (MAGIC). Eur J Vasc Endovasc Surg. 2016;52(6):758–63. https://doi.org/10.1016/j.ejvs.2016.09.007

4. Anagnostopoulos A, Mayer F, Ledergerber B, Bergadà-Pijuan J, Husmann L, Mestres CA, et al.; VASGRA Cohort Study. Editor's Choice — Validation of the Management of Aortic Graft Infection Collaboration (MAGIC) criteria for the diagnosis of vascular graft/endograft infection: results from the prospective Vascular Graft Cohort Study. Eur J Vasc Endovasc Surg. 2021;62(2):251–7. https://doi.org/10.1016/j.ejvs.2021.05.010

5. Reinders Folmer EI, Von Meijenfeldt GCI, Van der Laan MJ, Glaudemans AWJM, Slart RHJA, Saleem BR, et al. Diagnostic imaging in vascular graft infection: a systematic review and meta-analysis. Eur J Vasc Endovasc Surg. 2018;56(5):719–29. https://doi.org/10.1016/j.ejvs.2018.07.010

6. Riley DS, Barber MS, Kienle GS, Aronson JK, von Schoen-Angerer T, Tugwell P, et al. CARE guidelines for case reports: explanation and elaboration document. J Clin Epidemiol. 2017;89:218–35. https://doi.org/10.1016/j.jclinepi.2017.04.026

7. Samson RH, Veith FJ, Janko GS, Gupta SK, Scher LA. A modified classification and approach to the management of infections involving peripheral arterial prosthetic grafts. J Vasc Surg. 1988;8(2):147–53. https://doi.org/10.1016/0741-5214(88)90402-8

8. Szilagyi DE, Smith RF, Elliott JP, Vrandecic MP. Infection in arterial reconstruction with synthetic grafts. Ann Surg. 1972;176(3):321–33. https://doi.org/10.1097/00000658-197209000-00008

9. Oda T, Minatoya K, Kobayashi J, Okita Y, Akashi H, Tanaka H, et al. Prosthetic vascular graft infection through a median sternotomy: a multicentre review. Interact Cardiovasc Thorac Surg. 2015;20(5):701–6. https://doi.org/10.1093/icvts/ivv024

10. Umminger J, Krueger H, Beckmann E, Kaufeld T, Fleissner F, Haverich A, et al. Management of early graft infections in the ascending aorta and aortic arch: a comparison between graft replacement and graft preservation techniques. Eur J Cardiothorac Surg. 2016;50(4):660–7. https://doi.org/10.1093/ejcts/ezw150

11. LeMaire SA, Coselli JS. Options for managing infected ascending aortic grafts. J Thorac Cardiovasc Surg. 2007;134(4):839–43. https://doi.org/10.1016/j.jtcvs.2007.05.059

12. Tossios P, Karatzopoulos A, Tsagakis K, Sapalidis K, Triantafillopoulou K, Kalogera A, et al. Successful surgical in situ treatment of prosthetic graft infection by staged procedure after Bentall operation and total aortic arch replacement. Springerplus. 2014;3:172. https://doi.org/10.1186/2193-1801-3-172

13. Fujii T, Watanabe Y. Multidisciplinary treatment approach for prosthetic vascular graft infection in the thoracic aortic area. Ann Thorac Cardiovasc Surg. 2015;21(5):418–27. https://doi.org/10.5761/atcs.ra.15-00187

14. Joudinaud TM, Baron F, Raffoul R, Pagis B, Vergnat M, Parisot C, et al. Redo aortic root surgery for failure of an aortic homograft is a major technical challenge. Eur J Cardiothorac Surg. 2008;33(6):989–94. https://doi.org/10.1016/j.ejcts.2008.01.054

15. Kirali K, Sarikaya S, Ozen Y, Sacli H, Basaran E, Yerlikhan OA, et al. Surgery for aortic root abscess: a 15-year experience. Tex Heart Inst J. 2016;43(1):20–8. https://doi.org/10.14503/THIJ-14-4747

16. Lawrence PF. Conservative treatment of aortic graft infection. Semin Vasc Surg. 2011;24(4):199–204. https://doi.org/10.1053/j.semvascsurg.2011.10.014

17. FitzGerald SF, Kelly C, Humphreys H. Diagnosis and treatment of prosthetic aortic graft infections: confusion and inconsistency in the absence of evidence or consensus. J Antimicrob Chemother. 2005;56(6):996–9. https://doi.org/10.1093/jac/dki382

18. Smeds MR, Duncan AA, Harlander-Locke MP, Lawrence PF, Lyden S, Fatima J, et al. Treatment and outcomes of aortic endograft infection. J Vasc Surg. 2016;63(2):332–40. https://doi.org/10.1016/j.jvs.2015.08.113

19. Laohapensang K, Arworn S, Orrapin S, Reanpang T, Orrapin S. Management of the infected aortic endograft. Semin Vasc Surg. 2017;30(1):91–4. https://doi.org/10.1053/j.semvascsurg.2017.11.001

20. Raj R, Unnikrishnan D, Jacob A, Ashish K, Prakash A, Shah A. Periaortic abscess following DeBakey type-1 aortic dissection repair with Dacron graft — early diagnosis and management. Case Rep Cardiol. 2019;2019:6915356. https://doi.org/10.1155/2019/6915356

21. Xu L, Lin S, Yang Y. Perigraft abscess after DeBakey type-1 aortic dissection: a case report. J Cardiothorac Surg. 2020;15(1):94. https://doi.org/10.1186/s13019-020-01128-9

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Published

05/09/2026

How to Cite

Gabaidze, G., Nachkebiia, B., Kadjaia, M., Golomanidze, G., & Markoidze, M. (2026). Successful Management of a Periaortic Graft Abscess After DeBakey Type I Aortic Dissection Repair: A Case Report. Georgian Medical Journal, 1(2), 1–7. https://doi.org/10.66636/gmj.v1.i2.a118

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