Necrotising enterocolitis in a late-preterm infant with anastomotic dehiscence: a case report from Adjara, Georgia
DOI:
https://doi.org/10.66636/gmj.v1.i3.a190Keywords:
Necrotizing Enterocolitis, Gastrointestinal Emergency, Dehiscence, Preterm, Late-Preterm Infant, anastomotic dehiscence, neonatology, case reportAbstract
Background: Despite advances in the field of neonatal medicine, necrotising enterocolitis (NEC), a rapidly progressing disease characterised by ischaemia and bowel wall necrosis, remains a gastrointestinal emergency and a leading cause of morbidity and mortality among premature infants.
Case presentation: We report a case of a male infant born at 35 weeks and 4 days of gestation via caesarean section, due to a persistent non-reassuring fetal heart rate. The infant developed NEC complicated by terminal ileal perforation and diffuse peritonitis on day 13 of life, requiring an emergency exploratory laparotomy and stoma formation. On day 41, the postoperative course was further complicated by anastomotic dehiscence and recurrent pneumoperitoneum, necessitating a repeat surgical intervention with resection and secondary loop stoma creation. The infant made a full recovery and was discharged after stoma maturation. Normal growth parameters were documented at the two-month follow-up.
Conclusion: This case highlights the importance of considering NEC in the differential diagnosis of gastrointestinal complications in late-preterm infants, as early recognition and timely surgical intervention are crucial in reducing morbidity and improving clinical outcomes. This report also documents NEC for the first time in the region of Adjara, Georgia, where regional case-level reporting is currently unavailable, emphasising the need for regional clinical awareness.
Keywords: necrotising enterocolitis; gastrointestinal emergency; anastomotic dehiscence; late-preterm infant; neonatology; case report
References
1. Hu X, Liang H, Li F, Zhang R, Zhu Y, Zhu X, Xu Y. Necrotizing enterocolitis: current understanding of the prevention and management. Pediatr Surg Int. 2024;40:32. https://doi.org/10.1007/s00383-023-05619-3
2. Alsaied A, Islam N, Thalib L. Global incidence of Necrotizing Enterocolitis: a systematic review and meta-analysis. BMC Pediatr. 2020;20:344. https://doi.org/10.1186/s12887-020-02231-5
3. Van Varsseveld OC, Ten Broeke A, Chorus CG, Heyning N, Kooi EMW, Hulscher JBF. Surgery or comfort care for neonates with surgical necrotizing enterocolitis: lessons learned from behavioral artificial intelligence technology. Front Pediatr. 2023;11:1122188. https://doi.org/10.3389/fped.2023.1122188
4. Rose AT, Patel RM. A critical analysis of risk factors for necrotizing enterocolitis. Semin Fetal Neonatal Med. 2018;23(6):374–379. https://doi.org/10.1016/j.siny.2018.07.005
5. Nyenga AM, Mukuku O, Ziazia JS, Wembonyama SO. Necrotizing Enterocolitis in Preterm Infants: An Inflammatory Condition at the Crossroads of Intestinal Immaturity, Dysbiosis, and Nutrition. Int J Pediatr. 2026;1:9191604. https://doi.org/10.1155/ijpe/9191604
6. Sha C, Sander WR, Bass K, Hsieh H, Bialkowska AB. Necrotizing Enterocolitis: What's New and What's Next? Int J Mol Sci. 2025;26(19):9660. https://doi.org/10.3390/ijms26199660
7. Pammi M, Cope J, Tarr PI, Warner BB, Morrow AL, Mai V, et al. Intestinal dysbiosis in preterm infants preceding necrotizing enterocolitis: a systematic review and meta-analysis. Microbiome. 2017;5:31. https://doi.org/10.1186/s40168-017-0248-8
8. Bimerew M, Getie A, Gebreegziabher Araya F, Dessalegn N, Wondmieneh A, Ayalneh M. In-hospital mortality among neonates with necrotising enterocolitis in Ethiopia: a systematic review and meta-analysis. BMJ Open. 2024;14(12):e084003. https://doi.org/10.1136/bmjopen-2024-084003
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Sumithra Ramachandran, Uthayakumar Anandamohan, Yaren Dalyan, Nato Gorgadze

This work is licensed under a Creative Commons Attribution 4.0 International License.
This article is published open access under the Creative Commons Attribution 4.0 International (CC BY 4.0) licence.
You are free to: share and adapt the work for any purpose, even commercially.
Conditions: provide appropriate credit to the authors and the Georgian Medical Journal (GMJ), link to the licence, and indicate if changes were made. Do not apply legal terms or technological measures that legally restrict others from doing anything the licence permits.
Licence: creativecommons.org/licenses/by/4.0 · Legal code: creativecommons.org/licenses/by/4.0/legalcode
Third-party material. Images or other content credited to a third party are not covered by CC BY 4.0; permission must be obtained from the rights holder for reuse beyond statutory exceptions.
Authors' rights. Authors retain copyright. First publication rights are granted to GMJ.
Data and code. Where provided, datasets or code may carry their own licences; please follow the licence stated in the article or repository record.




















