Cardiovascular Screening in Pediatric Athletes: Prevalence, Risk Stratification, and Public Health Implications from a Georgian Population Cohort

Authors

DOI:

https://doi.org/10.5281/zenodo.19091480

Keywords:

Pediatric athletes, Sudden cardiac death, Preparticipation screening, Electrocardiography, Echocardiography, Risk stratification, Sports cardiology, Public health policy

Abstract

Background: Sudden cardiac death (SCD) in children and adolescents is a rare but catastrophic event with substantial societal and public health implications. A significant proportion of exercise-related SCD cases are attributable to previously undiagnosed structural or electrical cardiac abnormalities detectable through systematic screening [1–4]. Despite ongoing international debate regarding optimal screening models, region-specific epidemiological data remain limited in Eastern Europe and the Caucasus.

Objective: To determine the prevalence, clinical spectrum, and risk stratification profile of cardiovascular abnormalities identified during structured preparticipation screening of pediatric athletes in Adjara, Georgia, and to evaluate implications for national sports safety policy.

Methods: A population-based cross-sectional study was conducted in 2025 including 442 competitive athletes aged 7–18 years. All participants underwent standardized cardiovascular evaluation comprising structured medical history, physical examination, 12-lead electrocardiography interpreted according to contemporary international criteria, transthoracic echocardiography, and anthropometric assessment. Cardiovascular abnormalities were categorized into low-, intermediate-, and high-risk groups for SCD. Prevalence estimates were calculated with exact 95% confidence intervals (CI).

Results: Cardiovascular abnormalities were identified in 58 athletes (13.1%; 95% CI 10.1–16.6%). High-risk conditions were detected in 2 athletes (0.45%; 95% CI 0.05–1.6%), including one case of hypertrophic cardiomyopathy and one case of Wolff–Parkinson–White syndrome. The majority of abnormalities consisted of low-risk structural valvular findings. The number needed to screen to detect one high-risk condition was 221 athletes.

Conclusion: Systematic preparticipation cardiovascular screening in pediatric athletes reveals a measurable burden of clinically relevant structural and electrical abnormalities, including a small but significant proportion of high-risk conditions associated with exercise-related sudden cardiac events. The observed prevalence and detection yield are consistent with established international screening cohorts, suggesting comparable epidemiological patterns across diverse health system contexts.

While cross-sectional data do not permit inference regarding mortality reduction, these findings provide region-specific parameters necessary for proportional evaluation of screening strategies within organized youth sports. In emerging sports systems, such evidence supports informed and context-sensitive consideration of structured cardiovascular assessment frameworks aligned with available infrastructure and risk calibration.

 

Keywords: pediatric athletes; sudden cardiac death; cardiovascular screening; electrocardiography; echocardiography; risk stratification; public health policy

References

1. Winkel BG, Holst AG, Theilade J, Kristensen IB, Thomsen JL, Ottesen GL, et al. Sudden cardiac death in children and young adults: a nationwide study in Denmark. Eur Heart J. 2011;32(8):983–990. doi:10.1093/eurheartj/ehq428

2. Bagnall RD, Weintraub RG, Ingles J, Duflou J, Yeates L, Lam L, et al. A prospective study of sudden cardiac death among children and young adults. N Engl J Med. 2016;374(25):2441–2452. doi:10.1056/NEJMoa1510687

3. Maron BJ, Doerer JJ, Haas TS, Tierney DM, Mueller FO. Sudden deaths in young competitive athletes: analysis of 1866 deaths. Circulation. 2009;119(8):1085–1092. doi:10.1161/CIRCULATIONAHA.108.804617

4. Harmon KG, Asif IM, Klossner D, Drezner JA. Incidence of sudden cardiac death in NCAA athletes. Circulation. 2011;123(15):1594–1600. doi:10.1161/CIRCULATIONAHA.110.004622

5. Peterson DF, Kucera K, Thomas LC, Maleszewski JJ, Siebert DM, Lopez-Anderson M, et al. Aetiology and incidence of sudden cardiac arrest in young athletes. Br J Sports Med. 2021;55(5):258–264. doi:10.1136/bjsports-2020-102666

6. Corrado D, Basso C, Pavei A, Michieli P, Schiavon M, Thiene G. Trends in sudden cardiovascular death after screening. JAMA. 2006;296(13):1593–1601. doi:10.1001/jama.296.13.1593

7. Maron BJ, Thompson PD, Ackerman MJ, Balady G, Berger S, Cohen D, et al. Preparticipation cardiovascular screening of competitive athletes. Circulation. 2007;115(12):1643–1655. doi:10.1161/CIRCULATIONAHA.107.181423

8. Pelliccia A, Sharma S, Gati S, Bäck M, Börjesson M, Caselli S, et al. 2020 ESC Guidelines on sports cardiology. Eur Heart J. 2021;42(1):17–96. doi:10.1093/eurheartj/ehaa605

9. Sharma S, Drezner JA, Baggish A, Papadakis M, Wilson MG, Prutkin JM, et al. International recommendations for ECG interpretation in athletes. J Am Coll Cardiol. 2017;69(8):1057–1075. doi:10.1016/j.jacc.2017.01.015

10. Finocchiaro G, Papadakis M, Robertus JL, Dhutia H, Steriotis AK, Tome M, et al. Etiology of sudden death in sports. J Am Coll Cardiol. 2016;67(18):2108–2115. doi:10.1016/j.jacc.2016.02.062

11. Grazioli G, Merino B, Montserrat S, Vidal B, Azqueta M, Pare C, et al. Usefulness of echocardiography in screening athletes. Rev Esp Cardiol. 2014;67(9):701–705. doi:10.1016/j.rec.2013.11.023

12. Magalski A, McCoy M, Zabel M, Magee LM, Goeke J, Main ML, et al. Cardiovascular screening with ECG and echocardiography in athletes. Am J Med. 2011;124(6):511–518. doi:10.1016/j.amjmed.2011.01.009

13. Price DE, McWilliams A, Asif IM, Martin A, Elliott SD, Dulin M, et al. ECG-inclusive screening strategies. Heart Rhythm. 2014;11(3):442–449. doi:10.1016/j.hrthm.2013.12.002

14. Chandra N, Bastiaenen R, Papadakis M, Sharma S. Sudden cardiac death in young athletes. J Am Coll Cardiol. 2013;61(10):1027–1040. doi:10.1016/j.jacc.2012.08.1032

15. Corrado D, Basso C, Schiavon M, Thiene G. Screening for hypertrophic cardiomyopathy. N Engl J Med. 1998;339(6):364–369. doi:10.1056/NEJM199808063390602

16. Maron BJ, Levine BD, Washington RL, et al. Eligibility and disqualification recommendations. Circulation. 2015;132(22):e256–e261. doi:10.1161/CIR.0000000000000236

17. Corrado D, Pelliccia A, Bjørnstad HH, et al. European screening protocol. Eur Heart J. 2005;26(5):516–524. doi:10.1093/eurheartj/ehi108

18. Asif IM, Harmon KG. Incidence and etiology of sudden cardiac death. Sports Health. 2017;9(4):268–279. doi:10.1177/1941738116678493

19. Gersh BJ, Maron BJ, Bonow RO, et al. Hypertrophic cardiomyopathy guideline. J Am Coll Cardiol. 2011;58(25):e212–e260. doi:10.1016/j.jacc.2011.06.011

20. Semsarian C, Ingles J, Maron MS, Maron BJ. Hypertrophic cardiomyopathy insights. J Am Coll Cardiol. 2015;65(12):1249–1254. doi:10.1016/j.jacc.2015.01.019

21. O’Mahony C, Jichi F, Pavlou M, Monserrat L, Anastasakis A, Rapezzi C, et al. Risk prediction in HCM. Eur Heart J. 2014;35(30):2010–2020. doi:10.1093/eurheartj/eht439

22. Marcus FI, McKenna WJ, Sherrill D, et al. ARVC diagnosis. Circulation. 2010;121(13):1533–1541. doi:10.1161/CIRCULATIONAHA.108.840827

23. Sawant AC, Bhonsale A, te Riele ASJM, et al. Exercise and ARVC risk. J Am Coll Cardiol. 2014;64(14):1487–1494. doi:10.1016/j.jacc.2014.06.1193

24. Towbin JA, McKenna WJ, Abrams DJ, et al. Arrhythmogenic cardiomyopathy consensus. Heart Rhythm. 2019;16(11):e301–e372. doi:10.1016/j.hrthm.2019.05.007

25. de Onis M, Onyango AW, Borghi E, Siyam A, Nishida C, Siekmann J. WHO growth reference. Bull World Health Organ. 2007;85(9):660–667. doi:10.2471/BLT.07.043497

26. Drezner JA, Sharma S, Baggish A, Papadakis M, Wilson MG, Prutkin JM, et al. ECG interpretation criteria. Br J Sports Med. 2017;51(9):704–731. doi:10.1136/bjsports-2016-097331

27. Nishimura RA, Otto CM, Bonow RO, et al. Valvular heart disease guideline update. Circulation. 2017;135(25):e1159–e1195. doi:10.1161/CIR.0000000000000503

28. Wheeler MT, Heidenreich PA, Froelicher VF, Hlatky MA, Ashley EA. Cost-effectiveness of screening. Ann Intern Med. 2010;152(5):276–286. doi:10.7326/0003-4819-152-5-201003020-00005

29. Pappone C, Vicedomini G, Manguso F, et al. Wolff–Parkinson–White syndrome. Circulation. 2014;130(9):811–819. doi:10.1161/CIRCULATIONAHA.113.007799

30. Schwartz PJ, Crotti L, Insolia R. Long QT syndrome. Circ Arrhythm Electrophysiol. 2012;5(4):868–877. doi:10.1161/CIRCEP.111.962019

31. Brugada J, Campuzano O, Arbelo E, et al. Brugada syndrome. Eur Heart J. 2018;39(21):1741–1749. doi:10.1093/eurheartj/ehy129

32. Yamagata K, Horie M. Channelopathies. J Arrhythm. 2016;32(4):273–281. doi:10.1016/j.joa.2016.03.002

33. Ackerman MJ, Priori SG, Willems S, et al. Genetic testing in channelopathies. Europace. 2011;13(8):1077–1109. doi:10.1093/europace/eur245

34. Pelliccia A, Maron BJ, Di Paolo FM, et al. Athlete’s heart. J Am Coll Cardiol. 2005;45(8):1345–1352. doi:10.1016/j.jacc.2005.01.036

35. Sheikh N, Papadakis M, Ghani S, et al. ECG interpretation comparison. Br J Sports Med. 2014;48(15):1159–1165. doi:10.1136/bjsports-2014-093876

36. Malhotra A, Dhutia H, Finocchiaro G, et al. Outcomes of screening. N Engl J Med. 2018;379(6):524–534. doi:10.1056/NEJMoa1714719

37. Fuller CM. Cost-effectiveness of screening athletes. Med Sci Sports Exerc. 2000;32(5):887–890. doi:10.1097/00005768-200005000-00004

38. Welch HG, Black WC. Overdiagnosis. J Natl Cancer Inst. 2010;102(9):605–613. doi:10.1093/jnci/djq099

39. Zipes DP, Link MS, Ackerman MJ, et al. Athlete eligibility guidelines. Circulation. 2015;132(22):e273–e280. doi:10.1161/CIR.0000000000000240

40. Sharma S, Merghani A, Mont L. Exercise and the heart. Eur Heart J. 2015;36(23):1445–1453. doi:10.1093/eurheartj/ehv090

41. Asif IM, Drezner JA. Screening debate. Br J Sports Med. 2012;46(Suppl 1):i16–i23. doi:10.1136/bjsports-2012-091095

42. Harmon KG, Drezner JA, Wilson MG, et al. SCD in athletes. Br J Sports Med. 2014;48(15):1185–1192. doi:10.1136/bjsports-2014-093872

43. Corrado D, Migliore F, Basso C, et al. Exercise and SCD. Eur Heart J. 2011;32(8):934–944. doi:10.1093/eurheartj/ehr017

44. Sabatino J, De Rosa R, Di Salvo G. Ethics in sports cardiology. Eur J Prev Cardiol. 2020;27(2):112–114. doi:10.1177/2047487319892284

45. von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP. STROBE statement. Lancet. 2007;370(9596):1453–1457. doi:10.1016/S0140-6736(07)61602-X

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Published

03/18/2026

How to Cite

Shervashidze, M. (2026). Cardiovascular Screening in Pediatric Athletes: Prevalence, Risk Stratification, and Public Health Implications from a Georgian Population Cohort. Georgian Medical Journal, 1(1), 115–135. https://doi.org/10.5281/zenodo.19091480

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